Case Of Primary Mucinous Apocrine Gland Adenocarcinoma Of The Eyelid

Fusae Kajita¹, Toshiyuki Oshitari¹, Jiro Yotsukura¹, Kaoru Asanagi¹, Takashi Kishimoto², Shuichi Yamamoto¹

¹Department of Ophthalmology and Visual Science. Chiba University Graduate School of Medicine, Chiba, Japan
²Department of Molecular Pathology. Chiba University Graduate School of Medicine, Chiba, Japan

Purpose
To present a Japanese patient with primary mucinous adenocarcinoma of the lower eyelid.

Methods
The patient was a 73 year-old man who had swelling of the left lower eyelid for two years. He was referred to our hospital as a chalazion. The clinical and histopathological records were reviewed.

Results
Surgical excision of the tumor was performed, and histopathological examination revealed mucinous adenocrcinoma arisen in apocrine gland. Postoperative MRI and PET examinations showed no metastases over the entire body. We performed complete surgical excision with histopathological confirmation of negative margins of resection. After the final histopathologic examination of the specimen, the patient was diagnosed with a primary mucinous adenocarcinoma arisen in apocrine gland of the left eyelid. After the surgery, no recurrence has been observed anywhere in his body.

Conclusion
Primary mucinous apocrine gland adenocarcinoma of the eyelid is extremely rare in Japan. Because clinical appearance of mucinous adenocarcinoma of the eyelid before surgery is variable, final diagnosis depends on histopathological examinations. Complete surgical excision should be recommended.