Case report
Colchicine treatment for steroid-resistant VKH disease
The first and successful case reported in Cipto Mangunkusumo Hospital: shall we follow it?

Muhammad Iqbal Sofyan, Soedarman Sjamsoe, Lukman Edwar, Made Susiyanti
Department of Ophthalmology, Faculty of Medicine University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia

Purpose: This case report is aimed to show the role of colchicine as additional immunosuppressive agent in steroid-resistant VKH disease.

Method: Male, 35 years old, with steroid-resistant VKH disease with bilateral exudative macular detachment. He received high dose steroid and second line immunosuppressive agent (Azathioprine) and did not show any improvement. Visual acuity was OD: 1/300 and OS: 3/60. Colchicine as third line agent then was given.

Results: Additional colchicine can improve the left eye to 6/6, but the right eye cannot be helped as ischemia of posterior segment had already occurred.

Conclusion: Colchicine as immunosuppressive agent may have a role for severe and steroid-resistant VKH disease.

Keywords: colchicine, Vogt-Koyanagi-Harada disease, steroid-resistant