A Comparative Study Of Visual Outcomes And Higher-Order Aberrations Of Conventional, Aspheric, Wavefront And Combined Wavefront Aspheric Myopic LASIK

1. Robert Ang
2. Gladness Martinez

Asian Eye Institute, Makati City, Philippines

Purpose: To compare the refractive, visual and aberrometry results of myopic LASIK using Zyoptix Conventional (TS Tissue Saving), Aspheric (TSA), Wavefront (PT Personalized) and combined Wavefront Aspheric (PTA) treatment algorithm.

Methods: This comparative study included 84 eyes in the TS, 86 eyes in the TSA and 65 eyes in both the PT and PTA groups. The 3-month postoperative data were compared. Statistical significance was determined using One-way ANOVA with p<0.05.

Results: At 3 months, 83% in TS, 78% in TSA, 91% in PT and 98% of eyes in PTA had high-contrast UDVA of 20/20. Ninety-three percent in TS, 81% in TSA, 80% in PT and 89% in PTA achieved low-contrast UDVA of 20/40 or better. Twenty-seven percent in TS, 47% in TSA, 33% in PT and 45% in PTA gained at least 1 line of low-contrast CDVA. The mean spherical equivalent was -0.04D in TS, -0.13D in TSA, –0.01D in PT and -0.05D in PTA group (p=0.15). Mean change in total HOA was 0.332 in TS, 0.155 in TSA, 0.159 in PT and 0.081 in PTA (p=0.00). Mean change in spherical aberration was 0.225, 0.056, 0.202 and 0.019 while the mean change in Q value was 0.69, 0.28, 0.65 and 0.36 in the TS, TSA, PT and PTA groups, respectively (p=0.00).

Conclusions: Refractive and visual outcomes were similar in the 4 treatment algorithms. TSA and PTA had less induction of HOA, lower spherical aberration, and had better preservation of corneal asphericity, which translated to more lines of low-contrast vision gained.